When Safely chip enemy health in lane

1. Q→
2. AutoEmpowered basic attack

Tip Damaging a champion with Q creates a ring around the target. Step outside it once to ready the passive empowered basic attack, then move back into range to attack without lingering inside the enemy's retaliation range.

When Full burst when a kill is available

1. EMark→
2. EDash→
3. Q→
4. AutoEmpowered basic attack→
5. RFirst→
6. RMissing-health finish

Tip Recast E to dash in, then use Q and the passive-empowered basic attack. Save R2 until the target is below 35% health to maximize its missing-health damage.

When Break vision and engage from stealth

1. WStealth→
2. EMark→
3. EDash→
4. Q→
5. AutoEmpowered basic attack→
6. RFirst→
7. RMissing-health finish

Tip W creates a shroud at the landing point and grants invisibility, movement speed, and energy inside it. A basic attack reveals Akali, so mark with E to set up the engage, use Q-empowered basic attack, then return to the shroud before choosing the next action.

When Close a gap or escape with the two-part R

1. RFirst→
2. Q→
3. AutoEmpowered basic attack→
4. EMark→
5. EDash→
6. RMissing-health finish

Tip Use R1 to pass through the target, then lower their health with Q, a passive basic attack, and both E casts. R2 deals more against missing health, so save it to finish—or aim away from the enemy to leave when the kill is not available.