When Safe lane poke and mana-efficient trades

1. Q→
2. Auto

Tip Q shatters on the first enemy and continues behind it, dealing the same damage and slow. When the opponent stands just behind a minion, hit that minion so the shard reaches the champion without walking into the frontline.

When Dive in with E to lock down a target or start a fight

1. EFirst cast→
2. ESecond cast→
3. WRoot→
4. Q→
5. RStun

Tip Recast E as the claw passes the target, then press W immediately on arrival to root nearby enemies. Follow with Q and cast R on the target for a 1.5-second stun and surrounding slow; do not delay R long enough for Flash to escape its cast range.

When Surprise-catch a key target just out of W range

1. Flash→
2. WRoot→
3. RStun→
4. Q

Tip W activates instantly around Lissandra, so Flash into the target and root immediately. Cast enemy-targeted R before the root expires to chain its stun, fitting Q inside the crowd-control window to minimize the chance of a miss.

When Survive focus fire after diving or bait a burst

1. WRoot→
2. Q→
3. RSelf-cast invulnerability

Tip After rooting and damaging nearby enemies with W-Q, self-cast R to enter stasis for 2.5 seconds, avoid targeting and damage, and heal. Its damage and slow radiate for 3 seconds, but engage only when E or allied help can get Lissandra out after stasis ends.