When Safe poke and trades in lane

1. AutoBasic attack→
2. QWeave→
3. AutoBasic attack

Tip Hitting the same champion twice within 4 seconds siphons Mist for bonus current-health damage, so use basic attack → Q → basic attack to produce the two hits quickly. Q passes through units and structures, slows enemies, and heals allies in its path, but it is not a full attack-timer reset.

When Full all-in once W lands

1. WRoot→
2. AutoBasic attack→
3. QWeave→
4. AutoBasic attack→
5. AutoBasic attack

Tip W roots 1 second after it hits, so weave basic attacks and Q during the delay, then finish with basic attacks once the root locks them.

When Flashing into W range for a surprise delayed root

1. FlashFlash→
2. WRoot→
3. AutoBasic attack→
4. QWeave→
5. RFinisher

Tip Senna has no dash, so Flash closes the gap and creates a better W angle, but the projectile still has to connect. R can then add global finishing damage while shielding allies across the map.

When Approaching under camouflage before setting up W's delayed root

1. EMist→
2. WRoot→
3. AutoBasic attack→
4. QWeave→
5. AutoBasic attack

Tip Inside E, Senna is camouflaged and allies become speed-boosted Wraiths, but nearby enemy champions, turrets, or True Sight reveal them. Do not treat it as guaranteed untargetability; approach from outside detection, then land W as the mist breaks for its delayed root and follow with basic attack → Q.