Swain's Demonic Ascension (R) drain out-damages Soraka's healing, and after rooting with Nevermove (E) his Death's Hand (Q) burst keeps pressuring her low health, winning the sustain war.

Sona has no dash and is vulnerable to Nevermove (E)'s returning root and pull. Vision of Empire (W) slows and reveals rather than roots, so Swain should land E first, then chain W and Death's Hand (Q) to keep her inside Demonic Ascension (R).

Lacking burst, Milio can't out-heal Swain's Death's Hand (Q) and Vision of Empire (W) poke plus Demonic Ascension (R) drain sustain, and Swain's tankiness shrugs off Milio's low damage.

Yuumi has no hard CC, so Swain freely shoves the lane and picks with Nevermove (E) and Vision of Empire (W), dominating extended fights with Demonic Ascension (R) drain sustain and high health.

Blitzcrank's Rocket Grab (Q) yanks the immobile Swain out of position, and the follow-up Power Fist (E) burst cuts him down before Demonic Ascension (R) drain can even activate.

The immobile Swain can't dodge Pyke's Bone Skewer (Q) pull and Death From Below (R) execute, and even Demonic Ascension (R) drain sustain means nothing against the execute.

Leona chains CC with Zenith Blade (E) dash, Shield of Daybreak (Q) stun, and Solar Flare (R) root to lock Swain down, finishing him with burst before he can turn on Demonic Ascension (R) drain.

After hooking with Dredge Line (Q), Nautilus keeps the immobile Swain locked with repeated CC from Staggering Blow (P) and Depth Charge (R) to secure a guaranteed kill.

Thresh picks off the immobile Swain with Death Sentence (Q) hook and Flay (E), landing a powerful engage together with his ADC.