Zyra dominates range with Deadly Spines (Q) and Rampant Growth (W) plants, then roots with Grasping Roots (E) and airborne-CCs with Stranglethorns (R) to burst down the immobile Sona.

Zyra's sustained poke from Deadly Spines (Q) and Rampant Growth (W) plants outpaces the healing of Soraka's Starcall (Q), and Grasping Roots (E) punishes Soraka standing still to heal.

Yuumi lacks CC to threaten Zyra, so Zyra uses Rampant Growth (W) plants and Grasping Roots (E) to one-sidedly pressure the attached ADC and dominate the poke war.

Milio has no hard CC to threaten a kill on Zyra, and is forced to keep burning heals and shields against Rampant Growth (W) plant poke, losing the lane.

Leona closes in with Zenith Blade (E), then locks down the immobile Zyra with Shield of Daybreak (Q) stun into Solar Flare (R), killing her instantly.

Zyra has no mobility to escape Nautilus's long CC chain of Dredge Line (Q), Riptide (E), and the Staggering Blow (P) root, and gets bursted down.

A single Rocket Grab (Q) drags a caught Zyra in before she can set up plants, and the Power Fist (E) knockup combo instantly kills her.

Pyke pressures Zyra with Bone Skewer (Q) poke hooks and roams, then instantly finishes a low-health Zyra with Death From Below (R).

Thresh pins the immobile Zyra with the Death Sentence (Q) hook and Flay (E), setting her up for the ADC to kill.