With no mobility, Sona eats Ashe's Volley (W) poke layered with Frost Shot (P) slows, and gets locked into an initiation by Enchanted Crystal Arrow (R).

Ashe's constant Frost Shot (P) slows and Volley (W) poke chip away at Soraka's healing sustain, and lacking mobility she gets caught cleanly by Enchanted Crystal Arrow (R).

The moment Yuumi unattaches she has zero defensive tools and is instantly punished by Ashe's Frost Shot (P) slow and Volley (W) poke, and even while attached Ashe keeps whittling down her carry.

Milio is a mobility-less healer who gets initiated on by Ashe's Enchanted Crystal Arrow (R), and his short range loses the Volley (W) poke war.

When Leona dives in with Zenith Blade (E) and chains CC into Solar Flare (R), the mobility-less Ashe is pinned down and killed.

When Nautilus links his Dredge Line (Q) hook into a Staggering Blow (P) root, the CC chain leaves Ashe with no escape.

Caught by Blitzcrank's Rocket Grab (Q), the mobility-less Ashe has no way to dodge and gets dragged in and killed.

Pyke pressures with Bone Skewer (Q) pulls and all-ins and carries the Death From Below (R) execute, so the squishy, escape-less Ashe can't survive.

The mobility-less Ashe is reliably rooted by Lux's Light Binding (Q) and falls behind in lane to the ensuing full-combo poke.