Yasuo's Wind Wall (W) can block Crescent Strike (Q), so Diana engages after the wall is down. Once Q applies Moonlight, Lunar Rush (E), Pale Cascade (W)'s shield, and Moonfall (R)'s pull keep the melee fight going long enough to land Moonsilver Blade (P)'s third-hit magic damage.

Kassadin's lane is very weak until he unlocks Riftwalk (R) at level 5, so Diana pressures early with her Crescent Strike (Q) into Lunar Rush (E) reset all-in. Her Pale Cascade (W) shield also absorbs Null Sphere (Q) poke.

Veigar has no dash, so once Crescent Strike (Q) lands its Moonlight mark he can't escape the Lunar Rush (E) all-in, and Moonfall (R) pulls him in to confirm the combo. His only out is the Event Horizon (E) stun.

Orianna has no dash, so Diana tanks her Command: Attack (Q) ball poke with the Pale Cascade (W) shield, then closes with Lunar Rush (E) and pulls with Moonfall (R) to delete her. Once Diana hits her spike level, the all-in is guaranteed.

Aurelion Sol is weak early and lacks mobility, so Diana cuts him down with a Crescent Strike (Q) into Lunar Rush (E) into Moonfall (R) all-in before he stacks up his stars.

Zed uses Living Shadow (W) to dodge Crescent Strike (Q) and reposition, wearing Diana down in lane with energy-based poke. He turns her all-in around with Death Mark (R).

Fizz uses the untargetability of Playful / Trickster (E) to shrug off Diana's Moonfall (R) pull and Lunar Rush (E) dash, then out-bursts her with faster damage.

Talon has a strong early lane, overwhelming Diana with Rake (W) ranged poke and Noxian Diplomacy (Q) melee combos, and he seizes tempo with wall-hopping roams via Assassin's Path (E).

Pantheon dominates early skirmishes with the Shield Vault (W) leap-stun and Comet Spear (Q) poke, and his Aegis Assault (E) blocks Diana's first auto or ability to neutralize her all-in timing.