When Trading safely in lane to build a health lead

1. QSlow→
2. AutoPix trigger

Tip After Q applies its heavy decaying slow, a basic attack causes Pix to fire three extra bolts. Those bolts can be blocked by other units, so attack from a clear angle and return to safety before the slow ends.

When Saving a dived or focused ally carry

1. EShield→
2. WSpeed buff→
3. RKnock up

Tip Shield the ally with E and attach Pix, then place W's ring along their path; allies gain movement and attack speed while an entering enemy is prioritized for polymorph. If the diver is already on top of them, use R for bonus health and a knock-up, spacing the polymorph and knock-up instead of overlapping them.

When Ganking or catching a single enemy on the side

1. WPolymorph→
2. QSlow→
3. AutoBasic attack→
4. EFinish

Tip Polymorph to lock the target down, Q to stop their escape, then land a basic attack and E to finish. Damage still applies during polymorph.

When Enlarging a frontline ally to open a teamfight

1. RKnock up→
2. WPolymorph→
3. QSlow→
4. EDamage→
5. AutoBasic attack

Tip Cast R on an ally amid the enemies to knock them up, polymorph the biggest threat, then chain Q, E, and basic attacks for follow-up damage.