When Leona dashes in with Zenith Blade (E) and tries to stun with Shield of Daybreak (Q), Lulu polymorphs her with Whimsy (W) to cut the dive, then knocks up and heals the ally with Wild Growth (R) to neutralize the all-in.

When Nautilus pulls in with Dredge Line (Q) or follows up after popping a target with Depth Charge (R), Lulu polymorphs him with Whimsy (W) to break the CC chain, then knocks up and heals the caught ally with Wild Growth (R) to neutralize the all-in.

When Pyke hooks with Bone Skewer (Q) or looks for a finish with Death From Below (R), Lulu disarms him with Whimsy (W), and the Help, Pix! (E) shield plus Wild Growth (R) heal push the ally past the execute threshold, erasing Pyke's pick.

After Blitzcrank's only engage, Rocket Grab (Q), Lulu cuts the Power Fist (E) knock-up and Static Field (R) silence combo with Whimsy (W), then saves the grabbed ally with Wild Growth (R) to neutralize the follow-up damage.

Morgana's Black Shield (E) blocks Lulu's Whimsy (W) polymorph and Wild Growth (R) knock-up CC, neutralizing her key poke and peel, and if caught by Dark Binding (Q) the squishy Lulu simply bursts down.

Brand's Pillar of Flame (W) into Sear (Q) combo detonates burn poke that keeps chipping at Lulu's short range and low health in lane, making the Help, Pix! (E) shield too little to hold on.

Zyra's plants along with Grasping Roots (E) roots and Deadly Spines (Q) poke deal sustained damage from beyond Lulu's range, overwhelming the lane with output the Help, Pix! (E) shield can't offset.

Vel'Koz's long-range Plasma Fission (Q) and Void Rift (W) poke safely whittle down Lulu from beyond her Glitterlance (Q) range, and even the Whimsy (W) movement speed can't close the gap, so she loses the lane one-sidedly.

Lux's Light Binding (Q) and Lucent Singularity (E) poke pressure Lulu from longer range, and once caught by Light Binding (Q) her combo instantly bursts the low-health Lulu.