Pull in with Apprehend (E), stack Hemorrhage (P) via Decimate (Q), disrupt melee-weak early Nasus's Siphoning Strike (Q) stack farming, then execute before his scaling with Noxian Guillotine (R).

Pressure short-range melee Kayle before her power spike throughout the laning phase with Apprehend (E) and Decimate (Q) Hemorrhage (P), and block her scaling entirely with Noxian Guillotine (R) executes.

Yasuo's Wind Wall (W) can't block Darius's non-projectile abilities; close in with Apprehend (E), fill Hemorrhage (P) to 5 stacks for the empower, then execute with Noxian Guillotine (R).

With no mobility, Sion gets caught by Apprehend (E) and can't dodge full Hemorrhage (P) stacks or a guaranteed Noxian Guillotine (R) execute in short trades.

Weak in melee and sustain before level 5, Kassadin gets shoved by repeated Apprehend (E) and Decimate (Q) Hemorrhage (P), and is executed by Noxian Guillotine (R) before his Riftwalk (R) spike.

Nullify Apprehend (E) and Noxian Guillotine (R) with Riposte (W), and offset Hemorrhage (P) damage with Duelist's Dance (P) vital sustain to win long trades.

Dodge Apprehend (E) with Tumble (Q), knock Darius away the instant he closes with Condemn (E), and kite safely with ranged autos.

Blinding Dart (Q) nullifies Darius's autos, breaking Hemorrhage (P) stack upkeep, while Toxic Shot (P) ranged poison denies his approach entirely.

Kite with mini-form ranged autos, and deny Apprehend (E) angles with mega-form Wallop (W) stun and GNAR! (R) knockback to break the all-in.

Dodge and stun combo autos with Counter Strike (E), and flip the all-in trade with Grandmaster-at-Arms (R) defensive stat boosts.