Soraka has no mobility, so once you close in and root her with Twisted Advance (W) she cannot escape, and Sap Magic (P)'s sustained healing wins the heal war against her.

Zyra is squishy, so the instant she is rooted by Twisted Advance (W) she is bursted down with the Bramble Smash (Q) knockback combo, and with no escape she cannot get out.

Immobile Sona is reliably locked down by Twisted Advance (W) and finished with Nature's Grasp (R) and autos, melting before she can retaliate.

Vel'Koz is a skillshot mage with no instant mobility, so once you close the gap and root with Twisted Advance (W) he dies before landing his combo.

In the early lane, closing in and rooting with Twisted Advance (W) leaves Senna no way to run, and Sap Magic (P)'s sustain lets you ignore her poke.

Morgana's Black Shield (E) completely blocks both the Twisted Advance (W) root and the Nature's Grasp (R) roots, so Maokai's engage simply does not land.

Janna uses Howling Gale (Q) and Monsoon (R) to interrupt and push away the Twisted Advance (W) dash engage, preventing Maokai from pinning her allies.

Milio uses Breath of Life (R) to cleanse the root and heal his ally, undoing the Twisted Advance (W) lockdown and neutralizing the engage.

Karma protects allies with the shield and movement speed from Inspire (E) empowered by Mantra (P), and wears Maokai down with Inner Flame (Q) poke before he can engage, neutralizing his single-target initiation.