Jinx has no mobility, so Samira dashes in with Wild Rush (E), destroys the Zap! (W) and Flame Chompers! (E) projectiles with Blade Whirl (W), and finishes with Inferno Trigger (R).

Kog'Maw has short base range and no mobility, so Samira enters with Wild Rush (E) and bursts him down with her melee combo.

Samira's Blade Whirl (W) destroys Ashe's Volley (W) and Ranger's Focus (Q) projectiles, and the Frost Shot (P) slow alone can't withstand her Wild Rush (E) all-in.

Miss Fortune has no mobility, and Samira's Blade Whirl (W) blocks the Bullet Time (R) barrage, letting her overwhelm her with a melee all-in.

Samira needs to be in melee for her combo, but Varus zones her with Piercing Arrow (Q) poke and Hail of Arrows (E) slow, then punishes her entry with the triple-stacked Blighted Quiver (W) detonation.

Lucian overpowers Samira in early ranged trades with Lightslinger (P) double shots and Relentless Pursuit (E) dashes, dominating the lane with poke.

Caitlyn's longest range plus Yordle Snap Trap (W) and Piltover Peacemaker (Q) poke push Samira out of lane, chipping her health before she can stack Daredevil Impulse (P) Style or close the gap.

Ezreal pokes safely with Mystic Shot (Q) and dodges Samira's engage combo with Arcane Shift (E), neutralizing her all-in.

Draven's Spinning Axe (Q) gives him higher raw damage in early melee trades, winning the short-range exchanges Samira wants.